ADCY2

ADCY2
Dynodwyr
Cyfenwau	ADCY2, AC2, HBAC2, adenylate cyclase 2 (brain), adenylate cyclase 2
Dynodwyr allanol	OMIM: 103071 HomoloGene: 75133 GeneCards: ADCY2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • manganese ion binding • adenylate cyclase binding • metal ion binding • lyase activity • protein heterodimerization activity • phosphorus-oxygen lyase activity • ATP binding • magnesium ion binding • guanylate cyclase activity • adenylate cyclase activity Cydrannau o'r gell • cytoplasm • integral component of membrane • bilen • Cellbilen • integral component of plasma membrane • intracellular anatomical structure • dendrite • membrane raft • guanylate cyclase complex, soluble Prosesau biolegol • GO:0007243 intracellular signal transduction • cellular response to forskolin • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • cellular response to glucagon stimulus • cyclic nucleotide biosynthetic process • renal water homeostasis • cAMP biosynthetic process • cGMP biosynthetic process • GO:0072468 signal transduction • adenylate cyclase-activating G protein-coupled receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • cAMP-mediated signaling • G protein-coupled receptor signaling pathway • activation of adenylate cyclase activity • activation of protein kinase A activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	108	n/a
Ensembl	ENSG00000078295	n/a
UniProt	Q08462	n/a
RefSeq (mRNA)	NM_020546	n/a
RefSeq (protein)	NP_065433	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ADCY2 yw ADCY2 a elwir hefyd yn Adenylate cyclase type 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5p15.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ADCY2.

• AC2
• HBAC2

Llyfryddiaeth

• "Clinical validation study of genetic markers for capecitabine efficacy in metastatic colorectal cancer patients. ". Pharmacogenet Genomics. 2015. PMID 25815774.
• "Non-raft adenylyl cyclase 2 defines a cAMP signaling compartment that selectively regulates IL-6 expression in airway smooth muscle cells: differential regulation of gene expression by AC isoforms. ". Naunyn Schmiedebergs Arch Pharmacol. 2014. PMID 24363043.
• "AKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complex. ". Biochem J. 2013. PMID 23889134.
• "Interaction of the two cytosolic domains of mammalian adenylyl cyclase. ". Proc Natl Acad Sci U S A. 1996. PMID 8692867.
• "Different chromosomal localization of two adenylyl cyclase genes expressed in human brain.". Hum Genet. 1992. PMID 1427768.