ALDOB

ALDOB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1QO5, 1XDL, 1XDM
Dynodwyr
Cyfenwau	ALDOB, Aldob, Aldo-2, Aldo2, BC016435, ALDB, aldolase, fructose-bisphosphate B
Dynodwyr allanol	OMIM: 612724 HomoloGene: 20060 GeneCards: ALDOB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • fructose-1-phosphate aldolase activity • ATPase binding • cytoskeletal protein binding • fructose binding • GO:0001948, GO:0016582 protein binding • catalytic activity • lyase activity • identical protein binding • fructose-bisphosphate aldolase activity Cydrannau o'r gell • cytoplasm • centriolar satellite • microtubule organizing center • extracellular exosome • Cytosgerbwd • cytosol Prosesau biolegol • gluconeogenesis • positive regulation of ATP-dependent activity • glycolytic process • vacuolar proton-transporting V-type ATPase complex assembly • canonical glycolysis • fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate • fructose 1,6-bisphosphate metabolic process • NADH oxidation • fructose metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	229	n/a
Ensembl	ENSG00000136872	n/a
UniProt	P05062	n/a
RefSeq (mRNA)	NM_000035	n/a
RefSeq (protein)	NP_000026	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ALDOB yw ALDOB a elwir hefyd yn Aldolase, fructose-bisphosphate B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9q31.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ALDOB.

• ALDB
• ALDO2

Llyfryddiaeth

• "Aldolase B knockdown prevents high glucose-induced methylglyoxal overproduction and cellular dysfunction in endothelial cells. ". PLoS One. 2012. PMID 22911800.
• "Stabilization of the predominant disease-causing aldolase variant (A149P) with zwitterionic osmolytes. ". Biochemistry. 2011. PMID 21166391.
• "Aldolase B Overexpression is Associated with Poor Prognosis and Promotes Tumor Progression by Epithelial-Mesenchymal Transition in Colorectal Adenocarcinoma. ". Cell Physiol Biochem. 2017. PMID 28558381.
• Hereditary Fructose Intolerance. 1993. PMID 26677512.
• "ALDOB acts as a novel HBsAg-binding protein and its coexistence inhibits cisplatin-induced HepG2 cell apoptosis.". Crit Rev Eukaryot Gene Expr. 2014. PMID 25072145.